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Prostate Specific Antigen

Prostate Specific Antigen (PSA), is a protein secreted by the acinar cells of the Prostate, and is highly specific for the Prostate. Serum PSA levels are useful for determining the extent of Prostate Cancer, and assessing the response to therapy. However, it is NOT Prostate cancer specific, and other conditions such as: Benign Prostatic hyperplasia (BPH) or Prostatitis can affect PSA levels.

PSA is commonly used as a tool to detect Prostate Cancer, but its role in screening programmes is widely debated and controversial.

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